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Winston-Salem is a city in the U.S. state of North Carolina. Winston-Salem is also the county seat and largest city of Forsyth County and the fourth-largest city in the state. Winston-Salem is a prominent municipality in the Piedmont Triad region and is home to some of the tallest office buildings in the region, the Wachovia Center (Winston-Salem). It is often referred to as the "Twin City" for its dual heritage, although "Camel City" is another popular nickname, referring to the city's prominent tobacco industry (after Camel cigarettes). Many locals, however, use the shortened name "Winston" in informal speech. Winston-Salem is home to two universities; Wake Forest University, a nationally distinguished private university and Winston-Salem State University, an HBCU founded in 1892.